Study of arginase activity in serum of patients with hypothyroidism and type 2 diabetes mellitus

In L-arginine metabolizing pathways, arginase and nitric oxide synthase are regulated in a reciprocal manner. recent years, has been proposed as key player hyperthyroidism. The importance of arginine control not yet studied hypothyroidism. goal this study was to examine the activity type 2 diabetic patients with without two most popular endocrinopathies that exist clinical practice thyroid disease diabetes mellitus DM. hormones, on other hand, metabolism carbohydrates pancreas activity. group consisted 120 subjects divided into four groups; first included 30 healthy subjects, second both hypothyroidism DM, third (T2DM) fourth T2DM concentration fasting serum glucose (FSG), total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL), low (LDL), very low-density (VLDL), triiodothyronine (T3), thyroxin (T4), thyroid-stimulating hormone (TSH) were determined.